Genetic Engineering Will Change Everything Forever – CRISPR

  • Published: 10 August 2016
  • Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things will change irreversibly.

    Support us on Patreon so we can make more videos (and get cool stuff in return):

    Kurzgesagt merch here:

    Get the music of the video here:


    Thanks to Volker Henn, James Gurney and (prefers anonymity) for help with this video!


    Jeffrey Schneider, Konstantin Kaganovich, Tom Leiser, Archie Castillo, Russell Eishard, Ben Kershaw, Marius Stollen, Henry Bowman, Ben Johns, Bogdan Radu, Sam Toland, Pierre Thalamy, Christopher Morgan, Rocks Arent People, Ross Devereux, Pascal Michaud, Derek DuBreuil, Sofia Quintero, Robert Swiniarski, Merkt Kızılırmak, Michelle Rowley, Andy Dong, Saphir Patel, Harris Rotto, Thomas Huzij, Ryan James Burke, NTRX, Chaz Lewis, Amir Resali, The War on Stupid, John Pestana, Lucien Delbert, iaDRM, Jacob Edwards, Lauritz Klaus, Jason Hunt, Marcus : ), Taylor Lau, Rhett H Eisenberg, Mr.Z, Jeremy Dumet, Fatman13, Kasturi Raghavan, Kousora, Rich Sekmistrz, Mozart Peter, Gaby Germanos, Andreas Hertle, Alena Vlachova, Zdravko Šašek


    The best book we read about the topic: GMO Sapiens

    (affiliate link, we get a cut if buy the book!)

    – Good Overview by Wired:

    –timeline of computer development:

    – Selective breeding:

    – DNA:

    – Radiation research:

    – inserting DNA snippets into organisms:

    – First genetically modified animal:

    – First GM patent:

    – chemicals produced by GMOs:

    – Flavr Savr Tomato:

    – First Human Engineering:

    – glowing fish:

    – CRISPR:

    – HIV cut from cells and rats with CRISPR:

    – first human CRISPR trials fighting cancer:

    first human CRISPR trial approved by Chinese for August 2016:

    – genetic diseases:

    – pregnancies with Down Syndrome terminated:
    ( 1999 European study)

    – CRISPR and aging:

    Help us caption & translate this video!

Comments • 55 375

  • Kurzgesagt – In a Nutshell

    There's brand new stuff in the Kurzgesagt Merch Shop. Check it out here:

      UNIVERSE 3D  6 days back

      Nice your the best science youtuber

    • Leon Dorrenberg
      Leon Dorrenberg  3 weeks back

      Please make a video about homosexuality

    • Fire Of Game
      Fire Of Game  4 weeks back

      I want this amazing genetic engineering in my whole life
      If any bade want to be experiment with me
      Because I know the future is bright in genetic engineering
      I want to live forever

    • Cadence James
      Cadence James  4 weeks back

      Kurzgesagt – In a Nutshell
      We need a french kurzgesagt, please.

  • Azure Vox
    Azure Vox  5 hours back

    Turns out Hitler will get his dream in the end. We all know everyone, even non-white people are going to want their kids to have blue eyes and blonde hair!

    Not complaining, blonde girls are cute!

    • The Emerald Mage
      The Emerald Mage  6 hours back


      • Dog Lady
        Dog Lady  21 hours back

        This treatment will never be approved for anything because it’s not profitable and unfortunately that’s what everything is always about.

        • Bharat Kaushal
          Bharat Kaushal  22 hours back

          I think CAS9 is cute

          • Jayce Segler
            Jayce Segler  22 hours back

            Software and Genetic Engineers

            • AcautCandii
              AcautCandii  23 hours back

              Nah, let people die

              • La Lumière Huguenote
                La Lumière Huguenote  1 days back

                Terminate pregnancy. Another expression for killing a human life. "o but we do it ethically". Yea, k.

                • ratbag the weak
                  ratbag the weak  1 days back

                  The thing about trying to eliminate tons of diseases like cancer and the ones that kill lots of people, and trying to almost completely get rid of aging, overpopulation would be one of the biggest problem. Overpopulation is already a big problem right now, but imagine how much of a problem it would be if almost everyone died after 1000 years, and diseases have just been wiped off the table.

                  • • McKenna •
                    • McKenna •  1 days back

                    Yeah, but there’s the risk of off-target effects, and I’m not about that. There’s also a chance it doesn’t even work. What’s cool, though, is that there’s a gene drive that ensures the changed genes pass down through generations, which means less editing is needed. But with the off-target effects, Cas9 is led by an RNA guide and scientists don’t know where exactly it will end up, which can caused unexpected mutations. They have computers to predict where the protein ends up, but they can’t really calculate it and it can go anywhere, changing base pairs and the proteins that are made. A test was actually done on mice to cure blindness, which worked, but there were more than 200 unexpected mutations. It’s a fascinating technology, honestly.

                    • Adittya Abir Dhrubo
                      Adittya Abir Dhrubo  1 days back

                      0:24 adventure duck

                      • Aspire D
                        Aspire D  1 days back

                        "Its ok to have 4 arms, if everybody has 4 arms" -me

                        So yeah, this is why I think that the "warfare" side of this story will be fineee. Besides, what can a super human do vs a nuke?

                        • Aspire D
                          Aspire D  1 days back

                          9:07 I like the way he says the word "babies".

                          • Gijs Groote
                            Gijs Groote  1 days back

                            3:36 rick and mm*otherfuninnggg morthy

                            • TreyNitrotoluene
                              TreyNitrotoluene  2 days back

                              Today we complain about anti-vaxxers, tomorrow its anti-crispers.

                              • natty features EVERYTHING

                                i m not afraid this brought joyful tears to my eyes sadly this wont be available in time for my aunt who has stage 4 heart cancer.... i might not be able to save her life with it but i m going into this flied and i hope to save as many lives as i can that time and discovery will allow

                                • WorldOFwarcraftLIVE
                                  WorldOFwarcraftLIVE  2 days back

                                  herpes cure for the low low price of 200 treatment plans and doctor visits, no need for one shot though just drag it out like we do with chemotherapy

                                  • AshPlayz- Gaming and more!

                                    Can you design me a soul, coz I don't have one...

                                    • Calpeper Minutemen
                                      Calpeper Minutemen  2 days back


                                      • Ben Brooks
                                        Ben Brooks  2 days back

                                        Future be like:
                                        Johnny’s got a bout of pancreatic cancer so he’s staying home today, he should be back to Normal in a few days time!

                                        • Mihai Budau
                                          Mihai Budau  2 days back

                                          I have poor eyesight but extraordinary intelligence. So, does that mean that i am modified without a lab, if i was born in 2010?

                                          • J R42
                                            J R42  2 days back

                                            The world is not interested in curing cancer or HIV, because there is so much profit in bad treatments! Still, the question exists, if we were able to cure all diseases, can the Earth cope with more population growth?

                                            • Karl Jo
                                              Karl Jo  3 days back

                                              hope we can be free of diseases and die in a peaceful sleep

                                              • Dany Veiga
                                                Dany Veiga  3 days back

                                                well... that escalate quickly

                                                • Ducky McDuckface
                                                  Ducky McDuckface  3 days back

                                                  Ah bio-ethics, the bane of every bioscientific engineer

                                                  • Kid_Who_Plays _Drums_
                                                    Kid_Who_Plays _Drums_  3 days back

                                                    Maybe we can make the first real captain America serum but reallly just gene editing

                                                    • Graustreif 06
                                                      Graustreif 06  3 days back

                                                      I will be the first s Scientist in History to create a Fox Furry successful

                                                      • Raghu Seetharaman
                                                        Raghu Seetharaman  3 days back

                                                        At this point, we need a new college major called *Future Engineering* which produces a new profession called *Futuristic Research Scientist/Engineer.*

                                                        They can do research in AI, Transhumanism, Space Travel, Dyson Spheres, Solar Energy Use, etc. They reference science fiction directly as the foundation of inspiration for their research.

                                                        And Kurzgesagt is playing 24/7 at these research institutions.

                                                        • Paradox/Guy
                                                          Paradox/Guy  3 days back

                                                          Very cool, but why I am not glow in the dark?

                                                          • Mohammed Azeem
                                                            Mohammed Azeem  3 days back

                                                            So we can create customized human ?

                                                            • Blue Lightning Bug
                                                              Blue Lightning Bug  3 days back

                                                              Imagine a gene edited human that is completely perfect then applying a neural lace

                                                              • Abby Wachter
                                                                Abby Wachter  3 days back

                                                                i love this video thank you so much

                                                                • Sybyl7 1
                                                                  Sybyl7 1  3 days back

                                                                  These bioengineered people will may be born observed of certain desieses but , they will have a inferiority and much shortened life span . One can only look at other species that have been reduced with weakness . Let alone this a serious form of eugenics.

                                                                  • Outakantaï Gaming
                                                                    Outakantaï Gaming  4 days back

                                                                    Remind Seedship

                                                                    • Carlos Betancourt
                                                                      Carlos Betancourt  4 days back

                                                                      In other words,life is but a dream....

                                                                      • Dragón de 8 cabezas
                                                                        Dragón de 8 cabezas  4 days back

                                                                        I want to be a dragon :vvvvvvv

                                                                        • Dragón de 8 cabezas
                                                                          Dragón de 8 cabezas  4 days back

                                                                          If this happen while i'm still alive i'll be like;
                                                                          Plastic Surgeon: so what you wanna change
                                                                          Me: um i want like a tail and horns, scaily skin...

                                                                      • TUSezRUS
                                                                        TUSezRUS  4 days back


                                                                        • BossBabyPlayz
                                                                          BossBabyPlayz  4 days back

                                                                          12:23 is your marge. like to be pure blood.

                                                                          • The Bench
                                                                            The Bench  4 days back

                                                                            So it's getting cheap, so 50 yrs in the future someone with a understanding of this tech. could make a bio weapon in a lab in there basement??

                                                                            • Minh Khôi Phạm
                                                                              Minh Khôi Phạm  4 days back

                                                                              Nếu mọi người đều là siêu nhân thì thế giới sẽ không còn siêu nhân nữa

                                                                              • Tom Maitland
                                                                                Tom Maitland  4 days back

                                                                                Super human children can robots that take over with cross fire of aliens attacking and the sun exploding, thank you for the movie idea

                                                                                • Ryaken
                                                                                  Ryaken  4 days back

                                                                                  Skynet Judgement Day

                                                                                  • Aamir Hakeem
                                                                                    Aamir Hakeem  4 days back

                                                                                    Rick and Morty 3:34

                                                                                    • Bethlehem Eisenhour
                                                                                      Bethlehem Eisenhour  4 days back

                                                                                      Designer babies????? Jesus come soon, the world is about to become zombies that worship the devil.

                                                                                      • Cameron McIntosh
                                                                                        Cameron McIntosh  4 days back

                                                                                        if you read this your gay

                                                                                      • Nytes1982
                                                                                        Nytes1982  4 days back

                                                                                        13:41 Rick is trying to create a perfect Morty aye?

                                                                                        • Heshan Shibry
                                                                                          Heshan Shibry  4 days back

                                                                                          Great but if it goes to the wrong hands this will be more dangerous to all life everywhere.

                                                                                          • Princess SaraFina
                                                                                            Princess SaraFina  4 days back

                                                                                            Alright.. This is some Mad Scientist Shit.
                                                                                            Let's get this going